Antifertility Test of Maja Fruit Infusa (Aegle marmelos Corr) on Female White Rats (Rattus norvegicus)

Abstract

Contraceptives developed from natural materials are still very minimal, while the use of synthetic contraceptives in the community causes many complaints. Phytosterols in maja fruit are classified as steroids having a cyclopentanaperhydrophenanthrene ring shape, are estrogenic, and can affect follicular development and have anti-gonadotropic and anti-implantation effects, causing inhibition of ovulation and are anti-fertility. This study aims to determine the infusion of maja fruit has the potential as an anti-infertility against female white rats. This research method by grouping into 5 groups of female rats that have passed the fertility test then consisting of 2 control groups and 3 treatment groups... The antifertility effect on female white rats using Maja fruit infusa with a concentration of 2%, 5% and 10% given orally for 7 consecutive days. In all three treatments, the rats were infertile.